node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Kkor_1508 | Kkor_1605 | Kkor_1508 | Kkor_1605 | TIGRFAM: serine O-acetyltransferase; KEGG: pat:Patl_1236 serine O-acetyltransferase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.419 |
Kkor_1508 | Kkor_1765 | Kkor_1508 | Kkor_1765 | TIGRFAM: serine O-acetyltransferase; KEGG: pat:Patl_1236 serine O-acetyltransferase. | Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: ilo:IL0219 cystathionine gamma-synthase. | 0.859 |
Kkor_1508 | Kkor_1767 | Kkor_1508 | Kkor_1767 | TIGRFAM: serine O-acetyltransferase; KEGG: pat:Patl_1236 serine O-acetyltransferase. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ilo:IL0218 cysteine synthase B. | 0.972 |
Kkor_1508 | Kkor_2005 | Kkor_1508 | Kkor_2005 | TIGRFAM: serine O-acetyltransferase; KEGG: pat:Patl_1236 serine O-acetyltransferase. | Phosphoserine phosphatase SerB; KEGG: scl:sce0663 hypothetical protein; TIGRFAM: phosphoserine phosphatase SerB; HAD- superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.855 |
Kkor_1508 | glyA | Kkor_1508 | Kkor_0469 | TIGRFAM: serine O-acetyltransferase; KEGG: pat:Patl_1236 serine O-acetyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.848 |
Kkor_1508 | trpA | Kkor_1508 | Kkor_1642 | TIGRFAM: serine O-acetyltransferase; KEGG: pat:Patl_1236 serine O-acetyltransferase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.811 |
Kkor_1508 | trpB | Kkor_1508 | Kkor_1643 | TIGRFAM: serine O-acetyltransferase; KEGG: pat:Patl_1236 serine O-acetyltransferase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.810 |
Kkor_1605 | Kkor_1508 | Kkor_1605 | Kkor_1508 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: serine O-acetyltransferase; KEGG: pat:Patl_1236 serine O-acetyltransferase. | 0.419 |
Kkor_1605 | Kkor_1612 | Kkor_1605 | Kkor_1612 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-succinylhomoserine (thiol)-lyase; KEGG: asa:ASA_3795 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein. | 0.974 |
Kkor_1605 | Kkor_1765 | Kkor_1605 | Kkor_1765 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: ilo:IL0219 cystathionine gamma-synthase. | 0.974 |
Kkor_1605 | Kkor_1767 | Kkor_1605 | Kkor_1767 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ilo:IL0218 cysteine synthase B. | 0.940 |
Kkor_1605 | Kkor_1875 | Kkor_1605 | Kkor_1875 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: lpc:LPC_1632 adenosylhomocysteinase. | 0.949 |
Kkor_1605 | ahcY | Kkor_1605 | Kkor_0236 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.949 |
Kkor_1605 | glyA | Kkor_1605 | Kkor_0469 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.943 |
Kkor_1612 | Kkor_1605 | Kkor_1612 | Kkor_1605 | O-succinylhomoserine (thiol)-lyase; KEGG: asa:ASA_3795 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.974 |
Kkor_1612 | Kkor_1765 | Kkor_1612 | Kkor_1765 | O-succinylhomoserine (thiol)-lyase; KEGG: asa:ASA_3795 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein. | Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: ilo:IL0219 cystathionine gamma-synthase. | 0.907 |
Kkor_1612 | Kkor_1767 | Kkor_1612 | Kkor_1767 | O-succinylhomoserine (thiol)-lyase; KEGG: asa:ASA_3795 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ilo:IL0218 cysteine synthase B. | 0.966 |
Kkor_1612 | Kkor_1875 | Kkor_1612 | Kkor_1875 | O-succinylhomoserine (thiol)-lyase; KEGG: asa:ASA_3795 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein. | KEGG: lpc:LPC_1632 adenosylhomocysteinase. | 0.911 |
Kkor_1612 | ahcY | Kkor_1612 | Kkor_0236 | O-succinylhomoserine (thiol)-lyase; KEGG: asa:ASA_3795 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.915 |
Kkor_1765 | Kkor_1508 | Kkor_1765 | Kkor_1508 | Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: ilo:IL0219 cystathionine gamma-synthase. | TIGRFAM: serine O-acetyltransferase; KEGG: pat:Patl_1236 serine O-acetyltransferase. | 0.859 |