STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kkor_2115PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; PBS lyase HEAT domain protein repeat- containing protein; SMART: PBS lyase HEAT domain protein repeat- containing protein; KEGG: mxa:MXAN_4676 peptidylprolyl cis-trans isomerase, cyclophilin-type. (566 aa)    
Predicted Functional Partners:
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
 
 0.978
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
 
 0.959
Kkor_1788
PFAM: peptidylprolyl isomerase FKBP-type; FKBP-type peptidyl-prolyl isomerase domain protein; KEGG: amc:MADE_00743 FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (rotamase).
 
 0.946
Kkor_0531
TIGRFAM: elongation factor P-like protein YeiP; PFAM: Elongation factor P; Elongation factor P/YeiP protein; Elongation factor KOW domain protein; KEGG: plu:plu2861 elongation factor P.
  
 0.939
efp
Translation elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.
  
 0.939
truD
tRNA pseudouridine synthase D TruD; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
   
   0.878
Kkor_1161
KEGG: cja:CJA_2367 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase-associated domain protein; protein of unknown function DUF1605; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
   
 0.856
nuoH
NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
   
   0.833
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
  
 0.813
Kkor_2326
PFAM: peptidylprolyl isomerase FKBP-type; FKBP-type peptidyl-prolyl isomerase domain protein; KEGG: vsp:VS_2842 FkpA protein.
 
 0.809
Your Current Organism:
Kangiella koreensis
NCBI taxonomy Id: 523791
Other names: K. koreensis DSM 16069, Kangiella koreensis DSM 16069, Kangiella koreensis JCM 12318, Kangiella koreensis KCTC 12183, Kangiella koreensis SW-125, Kangiella koreensis str. DSM 16069, Kangiella koreensis strain DSM 16069
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