node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHY69412.1 | adk | SEHO0A_00447 | SEHO0A_00446 | Hypothetical protein. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.697 |
EHY69412.1 | hemH | SEHO0A_00447 | SEHO0A_00448 | Hypothetical protein. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.741 |
EHY69415.1 | hemH | SEHO0A_00450 | SEHO0A_00448 | Kinase, PfkB family; KEGG: set:SEN0472 2.7e-236 gsk; inosine-guanosine kinase; K00892 inosine kinase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM0491; gsk. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.793 |
adk | EHY69412.1 | SEHO0A_00446 | SEHO0A_00447 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Hypothetical protein. | 0.697 |
adk | hemH | SEHO0A_00446 | SEHO0A_00448 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.735 |
bfr | cyaY | SEHO0A_03530 | SEHO0A_04013 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.449 |
bfr | hemH | SEHO0A_03530 | SEHO0A_00448 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.992 |
cyaY | bfr | SEHO0A_04013 | SEHO0A_03530 | Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | 0.449 |
cyaY | hemH | SEHO0A_04013 | SEHO0A_00448 | Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.731 |
cyoE | hemH | SEHO0A_00396 | SEHO0A_00448 | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.992 |
hemA | hemC | SEHO0A_01768 | SEHO0A_04011 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
hemA | hemE | SEHO0A_01768 | SEHO0A_04256 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.900 |
hemA | hemH | SEHO0A_01768 | SEHO0A_00448 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.842 |
hemC | hemA | SEHO0A_04011 | SEHO0A_01768 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.996 |
hemC | hemE | SEHO0A_04011 | SEHO0A_04256 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.992 |
hemC | hemH | SEHO0A_04011 | SEHO0A_00448 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.783 |
hemE | hemA | SEHO0A_04256 | SEHO0A_01768 | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.900 |
hemE | hemC | SEHO0A_04256 | SEHO0A_04011 | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.992 |
hemE | hemG | SEHO0A_04256 | SEHO0A_04058 | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | KEGG: ses:SARI_03672 1.3e-94 hemG; protoporphyrinogen oxidase; K00230 protoporphyrinogen oxidase; locus tag in AE006468 is STM3987; hemG. | 0.815 |
hemE | hemH | SEHO0A_04256 | SEHO0A_00448 | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.979 |