STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHY69811.1Thiamine pyrophosphate enzyme, TPP binding domain protein; KEGG: stm:STM0935 0. poxB; pyruvate dehydrogenase K00156; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM0935; poxB; Belongs to the TPP enzyme family. (572 aa)    
Predicted Functional Partners:
nifJ
KEGG: sew:SeSA_A1770 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737; Psort location: CytoplasmicMembrane, score: 9.82; locus tag in AE006468 is STM1651; nifJ.
  
 
 0.996
EHY71550.1
Malate dehydrogenase; KEGG: sew:SeSA_A2705 0. maeB; malic enzyme K00029; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2472; maeB.
  
 
 0.994
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.993
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.991
pykF
Pyruvate kinase; KEGG: sei:SPC_2351 8.4e-242 pykF; pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1378; pykF.
  
 0.991
sfcA
Malic enzyme, NAD binding domain protein; KEGG: ses:SARI_01403 3.5e-291 malate dehydrogenase; K00027 malate dehydrogenase (oxaloacetate-decarboxylating); Psort location: CytoplasmicMembrane, score: 9.82; locus tag in AE006468 is STM1566; sfcA.
  
 
 0.991
ldhA
KEGG: set:SEN1405 7.3e-172 ldhA; D-lactate dehydrogenase; K03778 D-lactate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1647; ldhA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.991
pyk
Pyruvate kinase; Locus tag in AE006468 is STM1888; pykA; Belongs to the pyruvate kinase family.
  
 0.991
acs
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
   
 
 0.991
EHY69079.1
KEGG: see:SNSL254_A0129 7.2e-78 ilvH; acetolactate synthase, small subunit, isozyme III K01653; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM0117; ilvH.
 
 0.990
Your Current Organism:
Salmonella enterica houtenae
NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.