STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hprRTranscriptional activator protein Irlr; KEGG: rha:RHA1_ro05622 3.4e-39 response regulator (protein-glutamate methylesterase) K07669; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1096; copR. (226 aa)    
Predicted Functional Partners:
EHY69926.1
Heavy metal sensor kinase; Member of a two-component regulatory system.
 
 0.995
barA
ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; KEGG: sei:SPC_3015 0. barA; sensor protein; K07678 two-component system, NarL family, sensor histidine kinase BarA; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2958; barA.
 
0.945
EHY68118.1
TMAO reductase sytem sensor TorS; KEGG: set:SEN3642 0. torS; hybrid sensory histidine kinase TorS; K07647 two-component system, OmpR family, sensor histidine kinase TorS; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM3826; torS.
 
 0.908
arcB
PAS domain S-box; KEGG: sei:SPC_3398 0. arcB; aerobic respiration control sensor protein; K07648 two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM3328; arcB.
 
0.901
EHY71149.1
ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; KEGG: spq:SPAB_00894 7.5e-250 signal transduction histidine-protein kinase BaeS; K07642 two-component system, OmpR family, sensor histidine kinase BaeS; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2130; baeS.
 0.839
pmrB
ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; Locus tag in AE006468 is STM4291; basS.
 
 0.815
cpxA
ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; KEGG: ses:SARI_03586 8.4e-242 cpxA; two-component sensor protein; K07640 two-component system, OmpR family, sensor histidine kinase CpxA; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM4058; cpxA.
 0.808
EHY70256.1
ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; KEGG: sec:SC1413 0. ssrA; secretion system regulator:sensor component; K00873 pyruvate kinase K00936; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM1392; ssrA.
 
 0.792
nuoC
NADH dehydrogenase, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
   0.740
rcsC
ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
 0.731
Your Current Organism:
Salmonella enterica houtenae
NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.