STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpaHKEGG: sew:SeSA_A1169 3.9e-141 hpaH; 2-oxo-hepta-3-ene-1,7-dioic acid hydratase K02509; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1105; hpaH. (267 aa)    
Predicted Functional Partners:
EHY69932.1
4-hydroxyphenylacetate degradation isomerase/decarboxylase, subunit; KEGG: ses:SARI_01901 1.0e-227 hypothetical protein; K05921 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase.
 
 
 0.999
hpaI
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2- ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.
 
 0.999
hpcD
5-carboxymethyl-2-hydroxymuconate delta isomerase; KEGG: spq:SPAB_02449 2.4e-63 hypothetical protein; K01826 5-carboxymethyl-2-hydroxymuconate isomerase; locus tag in AE006468 is STM1104; hpaF.
 
 
 0.996
hpaD
3,4-dihydroxyphenylacetate 2,3-dioxygenase; KEGG: stm:STM1103 1.8e-154 hpaD; 4-hydroxyphenylacetate catabolism K00455; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1103; hpaD.
 
  
 0.995
hpaA
4-hydroxyphenylacetate catabolism regulatory protein HpaA; KEGG: lsp:Bsph_1999 5.1e-07 adaA; methylphosphotriester-DNA alkyltransferase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1108; hpaA.
 
    0.865
hpaR
Homoprotocatechuate degradation operon regulator, HpaR; KEGG: bpt:Bpet2634 1.1e-05 hpaH; 2-oxo-hept-3-ene-1,7-dioate hydratase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1100; hpaR.
 
     0.829
hpaX
KEGG: ecr:ECIAI1_4569 3.8e-223 putative 4-hydroxyphenylacetate permease HpaX K02511; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM1107; hpaX.
 
    0.785
hpaB
4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; KEGG: ses:SARI_01904 1.6e-286 hypothetical protein; K00483 4-hydroxyphenylacetate-3-hydroxylase large chain; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1099; hpaB.
 
   
 0.771
hpaE
KEGG: set:SEN0966 1.2e-260 hpaE; 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase (chms dehydrogenase) K00151; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1102; hpaE.
 
  
 0.739
EHY71058.1
HMGL-like protein; KEGG: plu:plu4081 7.2e-78 hypothetical protein; K01666 4-hydroxy 2-oxovalerate aldolase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.694
Your Current Organism:
Salmonella enterica houtenae
NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.