STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHY70219.1shortCoA ligase; KEGG: sec:SC1369 5.6e-284 ydiD; short chain acyl-CoA synthetase; K12507 acyl-CoA synthetase; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM1350; ydiD. (566 aa)    
Predicted Functional Partners:
entF
AMP-binding enzyme; KEGG: stm:STM0588 0. entF; enterobactin synthase subunit F; K02364 enterobactin synthetase component F; Psort location: CytoplasmicMembrane, score: 8.46; locus tag in AE006468 is STM0588; entF.
 
0.872
fadJ
Fatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.777
fadB
Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.777
EHY70221.1
FAD dependent oxidoreductase; Part of an electron transfer system. Belongs to the ETF-QO/FixC family.
  
  
 0.732
prpE
propionate--CoA ligase; KEGG: spq:SPAB_03225 0. prpE; propionyl-CoA synthetase; K01908 propionyl-CoA synthetase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0371; prpE.
 
0.705
acs
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
 
0.698
EHY68118.1
TMAO reductase sytem sensor TorS; KEGG: set:SEN3642 0. torS; hybrid sensory histidine kinase TorS; K07647 two-component system, OmpR family, sensor histidine kinase TorS; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM3826; torS.
  
  
 0.691
EHY68623.1
KEGG: ses:SARI_04585 0. methylmalonyl-CoA mutase; K01847 methylmalonyl-CoA mutase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.686
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
 0.683
barA
ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; KEGG: sei:SPC_3015 0. barA; sensor protein; K07678 two-component system, NarL family, sensor histidine kinase BarA; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2958; barA.
   
 
 0.679
Your Current Organism:
Salmonella enterica houtenae
NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.