STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumDHypothetical protein; Locus tag in AE006468 is STM1388; orf70. (70 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate.
     
  0.994
sfcA
Malic enzyme, NAD binding domain protein; KEGG: ses:SARI_01403 3.5e-291 malate dehydrogenase; K00027 malate dehydrogenase (oxaloacetate-decarboxylating); Psort location: CytoplasmicMembrane, score: 9.82; locus tag in AE006468 is STM1566; sfcA.
     
 0.991
EHY70332.1
Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.990
EHY71550.1
Malate dehydrogenase; KEGG: sew:SeSA_A2705 0. maeB; malic enzyme K00029; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2472; maeB.
     
 0.990
fumB
Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.990
frdD
Fumarate reductase subunit D; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
     
  0.954
frdC
Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
     
  0.954
frdB
Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Locus tag in AE006468 is STM4342; frdB; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
     
  0.954
frdA
Fumarate reductase, flavoprotein subunit; Locus tag in AE006468 is STM4343; frdA.
     
  0.954
ttrR
Transcriptional regulator, LuxR family; KEGG: acr:Acry_3169 8.4e-19 signal transduction histidine kinase with CheB and CheR activity; K00575 chemotaxis protein methyltransferase CheR K03412; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1387; ttrR.
     
 0.582
Your Current Organism:
Salmonella enterica houtenae
NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581
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