node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHY68884.1 | folB | SEHO0A_03384 | SEHO0A_03295 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
EHY68884.1 | folE | SEHO0A_03384 | SEHO0A_02292 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase I; KEGG: seg:SG2230 8.9e-112 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2193; folE. | 0.961 |
EHY68884.1 | folK | SEHO0A_03384 | SEHO0A_00179 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | KEGG: ses:SARI_02814 2.6e-73 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; K00950 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; locus tag in AE006468 is STM0183; folK. | 0.999 |
barA | folE | SEHO0A_03006 | SEHO0A_02292 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; KEGG: sei:SPC_3015 0. barA; sensor protein; K07678 two-component system, NarL family, sensor histidine kinase BarA; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2958; barA. | GTP cyclohydrolase I; KEGG: seg:SG2230 8.9e-112 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2193; folE. | 0.927 |
barA | mazG | SEHO0A_03006 | SEHO0A_03003 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; KEGG: sei:SPC_3015 0. barA; sensor protein; K07678 two-component system, NarL family, sensor histidine kinase BarA; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2958; barA. | MazG family protein; KEGG: sea:SeAg_B3087 2.7e-133 mazG; nucleoside triphosphate pyrophosphohydrolase; K02428 nucleoside-triphosphate pyrophosphatase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2954; mazG. | 0.924 |
barA | moaA | SEHO0A_03006 | SEHO0A_00749 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; KEGG: sei:SPC_3015 0. barA; sensor protein; K07678 two-component system, NarL family, sensor histidine kinase BarA; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2958; barA. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.942 |
barA | ndk | SEHO0A_03006 | SEHO0A_02695 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; KEGG: sei:SPC_3015 0. barA; sensor protein; K07678 two-component system, NarL family, sensor histidine kinase BarA; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2958; barA. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.937 |
barA | ribA | SEHO0A_03006 | SEHO0A_01695 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; KEGG: sei:SPC_3015 0. barA; sensor protein; K07678 two-component system, NarL family, sensor histidine kinase BarA; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2958; barA. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 0.929 |
folB | EHY68884.1 | SEHO0A_03295 | SEHO0A_03384 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
folB | folE | SEHO0A_03295 | SEHO0A_02292 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; KEGG: seg:SG2230 8.9e-112 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2193; folE. | 0.986 |
folB | folK | SEHO0A_03295 | SEHO0A_00179 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: ses:SARI_02814 2.6e-73 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; K00950 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; locus tag in AE006468 is STM0183; folK. | 0.999 |
folB | queD | SEHO0A_03295 | SEHO0A_02990 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 6-pyruvoyl tetrahydropterin synthase/QueD family protein; KEGG: sty:STY3077 2.5e-43 putative 6-pyruvoyl tetrahydrobiopterin synthase; K01737 6-pyruvoyl tetrahydrobiopterin synthase; locus tag in AE006468 is STM2949; ptpS. | 0.526 |
folE | EHY68884.1 | SEHO0A_02292 | SEHO0A_03384 | GTP cyclohydrolase I; KEGG: seg:SG2230 8.9e-112 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2193; folE. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.961 |
folE | barA | SEHO0A_02292 | SEHO0A_03006 | GTP cyclohydrolase I; KEGG: seg:SG2230 8.9e-112 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2193; folE. | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; KEGG: sei:SPC_3015 0. barA; sensor protein; K07678 two-component system, NarL family, sensor histidine kinase BarA; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2958; barA. | 0.927 |
folE | folB | SEHO0A_02292 | SEHO0A_03295 | GTP cyclohydrolase I; KEGG: seg:SG2230 8.9e-112 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2193; folE. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.986 |
folE | folK | SEHO0A_02292 | SEHO0A_00179 | GTP cyclohydrolase I; KEGG: seg:SG2230 8.9e-112 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2193; folE. | KEGG: ses:SARI_02814 2.6e-73 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; K00950 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; locus tag in AE006468 is STM0183; folK. | 0.995 |
folE | mazG | SEHO0A_02292 | SEHO0A_03003 | GTP cyclohydrolase I; KEGG: seg:SG2230 8.9e-112 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2193; folE. | MazG family protein; KEGG: sea:SeAg_B3087 2.7e-133 mazG; nucleoside triphosphate pyrophosphohydrolase; K02428 nucleoside-triphosphate pyrophosphatase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2954; mazG. | 0.925 |
folE | moaA | SEHO0A_02292 | SEHO0A_00749 | GTP cyclohydrolase I; KEGG: seg:SG2230 8.9e-112 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2193; folE. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.991 |
folE | ndk | SEHO0A_02292 | SEHO0A_02695 | GTP cyclohydrolase I; KEGG: seg:SG2230 8.9e-112 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2193; folE. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.931 |
folE | ntpA | SEHO0A_02292 | SEHO0A_01921 | GTP cyclohydrolase I; KEGG: seg:SG2230 8.9e-112 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2193; folE. | Hydrolase, NUDIX family; Locus tag in AE006468 is STM1900; ntpA. | 0.995 |