STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccmDHeme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (57 aa)    
Predicted Functional Partners:
ccmC_2
Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 
 0.943
ccmE
Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.937
EHY71315.1
Tetratricopeptide repeat protein; KEGG: pfo:Pfl01_1584 5.9e-28 diaminohydroxyphosphoribosylaminopyrimidine deaminase, 5-amino-6-(5-phosphoribosylamino) uracil reductase K02200; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM3812; ccmH.
 
  
 0.886
ccmB
Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
 
 0.867
EHY71316.1
Periplasmic protein thiol:disulfide oxidoreductase, DsbE family protein; KEGG: azo:azo3929 2.7e-30 ccmG; protein disulfide-isomerase K02199; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2248; ccmG.
 
  
 0.863
EHY71317.1
Cytochrome c-type biogenesis protein CcmF; KEGG: vfi:VF_1819 1.0e-213 ccmF; heme lyase, CcmF subunit K02198; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2249; ccmF.
  
  
 0.850
EHY68109.1
KEGG: vfi:VF_1822 1.1e-79 ccmC; heme exporter subunit C K02195; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2252; ccmC.
 
 
 0.840
ccmA
Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
 
 
 0.768
EHY68107.1
Cytochrome c-type biogenesis protein CcmE; KEGG: sec:SC3737 7.8e-65 ccmA; heme ABC exporter ATP-binding protein; K02193 heme exporter ATP-binding protein CcmA; locus tag in AE006468 is STM2250; ccmE.
 
 
 0.733
EHY68110.1
Heme exporter protein CcmB; Psort location: CytoplasmicMembrane, score: 10.00; locus tag in AE006468 is STM2253; ccmB.
 
 
 0.713
Your Current Organism:
Salmonella enterica houtenae
NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581
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