STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHY68440.1Type III secretion target, IpaC/SipC family; Locus tag in AE006468 is STM2884; sipC. (409 aa)    
Predicted Functional Partners:
EHY68438.1
Hypothetical protein; Locus tag in AE006468 is STM2882; sipA.
  
  
 0.999
sipB
Hypothetical protein; Locus tag in AE006468 is STM2885; sipB.
  
  
 0.999
sicA
Type III secretion low calcium response chaperone LcrH/SycD; Locus tag in AE006468 is STM2886; sicA.
  
  
 0.999
sopB
Enterobacterial virulence protein; Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enl [...]
   
  
 0.996
EHY68439.1
Type III effector protein IpaD/SipD/SspD; Locus tag in AE006468 is STM2883; sipD.
  
  
 0.995
sptP
Virulence determinant protein; Locus tag in AE006468 is STM2878; sptP.
  
  
 0.986
sopE2
SopE GEF domain protein; Locus tag in AE006468 is STM1855; sopE2.
   
  
 0.954
EHY68448.1
Surface presentation of antigens protein; Locus tag in AE006468 is STM2892; invJ.
  
  
 0.950
prgH
Type III secretion apparatus protein PrgH/EprH; Locus tag in AE006468 is STM2874; prgH.
   
  
 0.948
invG
Type III secretion outer membrane pore, YscC/HrcC family; Locus tag in AE006468 is STM2898; invG.
  
  
 0.948
Your Current Organism:
Salmonella enterica houtenae
NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.