STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nanRTranscriptional repressor NanR; Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids. (242 aa)    
Predicted Functional Partners:
nanT-2
MFS transporter, sialate:H+ symporter family protein; Catalyzes the proton-dependent transport of sialic acid. Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
 
   
 0.928
nanA
N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
 
   
 0.927
nanE-2
Putative N-acetylmannosamine-6-P epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
     
 0.879
EHY68923.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM3335; yhcH.
     
 0.859
nanK
ROK family protein; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily.
 
   
 0.753
EHY68830.1
Transcriptional regulator, GntR family; KEGG: hiq:CGSHiGG_02770 8.5e-52 D-mannonate oxidoreductase; Psort location: Cytoplasmic, score: 8.96.
  
     0.744
nadR
Nicotinamide-nucleotide adenylyltransferase; Locus tag in AE006468 is STM4580; nadR.
   
    0.570
EHY69812.1
2Fe-2S iron-sulfur cluster binding domain protein; KEGG: sew:SeSA_A1053 5.7e-172 hcr; HCP oxidoreductase, NADH-dependent K11933; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0936; hcr.
 
  
  0.524
ydfH
Transcriptional regulator, GntR family; KEGG: hiq:CGSHiGG_02770 5.2e-12 D-mannonate oxidoreductase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1510; ydfH.
  
  
 0.510
EHY68171.1
UbiC transcription regulator-associated; KEGG: bcz:BCZK3111 2.9e-19 GntR family transcriptional regulator K00837; Psort location: Cytoplasmic, score: 8.96.
  
    0.506
Your Current Organism:
Salmonella enterica houtenae
NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.