STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
korB2-oxoglutarate ferredoxin oxidoreductase, subunit beta. (287 aa)    
Predicted Functional Partners:
korA
2-oxoglutarate ferredoxin oxidoreductase, subunit alpha.
 
 0.999
porA
Pyruvate--ferredoxin oxidoreductase, alpha subunit.
 
 0.997
HFX_0998
acyl-CoA synthetase, acetate--CoA ligase-like protein (ADP-forming).
    
 0.948
sucD
succinate--CoA ligase, alpha subunit (ADP-forming); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.932
sucC
succinate--CoA ligase beta subunit (ADP-forming); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.930
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.925
citZ
Citrate (si)-synthase.
   
 
 0.923
pdhC
Dihydrolipoamide S-acyltransferase (pyruvate dehydrogenase E2 component).
   
 
 0.922
icd
Isocitrate dehydrogenase (NADP+).
     
 0.920
pdhD
Dihydrolipoamide dehydrogenase.
    
 0.919
Your Current Organism:
Haloferax mediterranei
NCBI taxonomy Id: 523841
Other names: H. mediterranei ATCC 33500, Haloferax mediterranei ATCC 33500, Haloferax mediterranei CGMCC 1.2087, Haloferax mediterranei JCM 8866, Haloferax mediterranei R-4, Haloferax mediterranei str. ATCC 33500, Haloferax mediterranei strain ATCC 33500
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