Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mscS-2Mechanosensitive ion channel. (396 aa)    
Predicted Functional Partners:
crcB
CRCB integral membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
     
 0.561
crcB-2
CRCB integral membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
     
 0.561
HFX_1238
Putative membrane-bound metal-dependent hydrolase.
       0.543
nmd3
Putative NMD protein affecting ribosome stability and mRNA decay.
   
    0.483
kefC
Potassium transport protein kefC.
 
   
 0.414
HFX_1239
Hypothetical protein.
       0.409
Your Current Organism:
Haloferax mediterranei
NCBI taxonomy Id: 523841
Other names: H. mediterranei ATCC 33500, Haloferax mediterranei ATCC 33500, Haloferax mediterranei CGMCC 1.2087, Haloferax mediterranei JCM 8866, Haloferax mediterranei R-4, Haloferax mediterranei str. ATCC 33500, Haloferax mediterranei strain ATCC 33500
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