STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
accAPropionyl-CoA carboxylase, carboxyltransferase subunit; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl- CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA (516 aa)    
Predicted Functional Partners:
accA2
Propionyl-CoA carboxylase, biotin carboxylase and biotin-carboxyl carrier subunit; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl- CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. PccA carries two functions: biotin carboxyl carrier [...]
 
 0.996
pccX
Propionyl-CoA carboxylase, protein PccX subunit; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl- CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. PccX could be responsible for the interaction of the biotin carboxylase and carboxylt [...]
     
 0.984
gloA
annotation not available
 
 
 0.963
HFX_2006
annotation not available
  
 
 0.924
HFX_0998
annotation not available
    
 0.918
HFX_0870
annotation not available
  
 
 0.916
HFX_1242
annotation not available
  
 
 0.916
HFX_1643
annotation not available
  
 
 0.916
acs4
annotation not available
  
 
 0.916
porB
annotation not available
     
  0.900
Your Current Organism:
Haloferax mediterranei
NCBI taxonomy Id: 523841
Other names: H. mediterranei ATCC 33500, Haloferax mediterranei, Haloferax mediterranei ATCC 33500, Haloferax mediterranei ATCC33500, Haloferax mediterranei CGMCC 1.2087, Haloferax mediterranei JCM 8866, Haloferax mediterranei R-4, Haloferax mediterranei str. ATCC 33500, Haloferax mediterranei strain ATCC 33500
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