STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (413 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 0.999
SMH35319.1
3-isopropylmalate dehydratase, small subunit.
 0.999
SMH30376.1
3-isopropylmalate dehydrogenase.
 0.969
SMH35313.1
3-isopropylmalate dehydrogenase.
 0.956
SMH28338.1
Pyruvate oxidase; Belongs to the TPP enzyme family.
  
 
 0.950
aksA
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.926
SMH31529.1
Isopropylmalate/homocitrate/citramalate synthases.
 
 
 0.914
SMH30236.1
2-isopropylmalate synthase; Non-canonical start codon; manually curated.
  
 
 0.910
SMH31525.1
Isocitrate dehydrogenase (NADP).
 0.906
SMH29097.1
(R)-citramalate synthase; Non-canonical start codon; manually curated.
  
 
 0.903
Your Current Organism:
Methanohalophilus portucalensis
NCBI taxonomy Id: 523843
Other names: M. portucalensis FDF-1, Methanohalophilus portucalensis DSM 7471, Methanohalophilus portucalensis FDF-1, Methanohalophilus portucalensis str. FDF-1, Methanohalophilus portucalensis strain FDF-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.