Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB11921.1Hypothetical protein. (464 aa)    
Predicted Functional Partners:
AKB13251.1
RecB family exonuclease.
  
     0.629
ef1b
Translation elongation factor 1 beta subunit; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
 
     0.618
AKB12496.1
Hypothetical protein.
 
     0.616
AKB14131.1
Oligosaccharyl transferase.
  
     0.615
AKB14179.1
Nucleotide binding protein, PINc.
  
     0.612
AKB12373.1
DNA-directed RNA polymerase subunit F.
  
     0.610
AKB13385.1
Zn-ribbon containing protein.
  
     0.606
AKB14130.1
Oligosaccharyl transferase.
  
     0.597
endA
tRNA-intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
 
     0.595
atpE
V-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
     0.585
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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