Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB11937.1Ribosomal-protein-S18p-alanine acetyltransferase. (142 aa)    
Predicted Functional Partners:
AKB11928.1
Molybdopterin-guanine dinucleotide biosynthesis protein MobB.
    
 
 0.532
rpl30e
LSU ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family.
 
   0.488
AKB12345.1
Phytol kinase.
  
     0.473
rps3
SSU ribosomal protein S3e (S3p); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 
 0.471
rps19e
SSU ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
 
   0.469
rpl18
LSU ribosomal protein L5e (L18p); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
   0.467
rps4
SSU ribosomal protein S9e (S4p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
   0.450
rpl13
LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.444
rpl5
LSU ribosomal protein L11e (L5p); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
  
   0.441
AKB11936.1
Nickel responsive regulator NikR; Transcriptional regulator.
       0.429
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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