Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB11983.1COG1821 family protein. (319 aa)    
Predicted Functional Partners:
AKB11984.1
Putative H4MPT-linked C1 transfer pathway protein.
 
  
 0.996
AKB11985.1
Delta 1-pyrroline-5-carboxylate synthetase.
 
   
 0.962
mfnA
L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
 
  
 0.922
mfnB
Duf556 family protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
 
   
 0.777
AKB13029.1
Formylmethanofuran dehydrogenase subunit A.
 
   
 0.750
AKB13524.1
Formylmethanofuran dehydrogenase subunit A.
 
   
 0.737
AKB14084.1
Methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase.
  
     0.719
ftr
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
     0.718
AKB12130.1
Formylmethanofuran dehydrogenase subunit B.
 
     0.715
AKB13030.1
Formylmethanofuran dehydrogenase subunit C.
 
     0.711
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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