Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB12016.13-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (236 aa)    
Predicted Functional Partners:
AKB11964.1
NADH-quinone oxidoreductase subunit C/D.
  
 
 0.849
AKB11965.1
NADH-quinone oxidoreductase subunit C/D.
  
 
 0.849
AKB13248.1
Beta-ketoacyl synthase/thiolase.
 
 
 0.797
AKB12142.1
Putative ankyrin repeat protein.
  
 0.795
AKB12273.1
Peptidyl-prolyl cis-trans isomerase.
 
 
 0.776
mre11
Exonuclease SbcD; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
  
 
 0.753
AKB13421.1
ATP-dependent DNA helicase RecQ.
 
 
 
 0.684
AKB13590.1
Two-component response regulator.
  
 
 0.651
AKB12496.1
Hypothetical protein.
 
 0.646
AKB12018.1
ABC transporter, ATP-binding protein.
 
 
 0.630
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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