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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB12242.1Response regulator receiver. (157 aa)    
Predicted Functional Partners:
AKB13590.1
Two-component response regulator.
 
 
 0.892
AKB13591.1
Methyl-accepting chemotaxis protein.
  
 
 0.811
AKB12611.1
Response regulator receiver.
 
 
 
 0.750
AKB12754.1
Sensory transduction histidine kinase.
   
 0.693
AKB13128.1
Sensory transduction histidine kinase.
 
 
 0.683
AKB12207.1
Sensory transduction histidine kinase.
   
 0.679
AKB12491.1
Sensory transduction histidine kinase.
   
 0.677
AKB12205.1
Sensory transduction histidine kinase.
   
 0.676
AKB13843.1
Sensory transduction histidine kinase.
 
 
 
 0.674
AKB13592.1
Positive regulator of CheA protein activity (CheW).
  
 
 0.671
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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