Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AKB12275.1Integral membrane protein. (291 aa)    
Predicted Functional Partners:
AKB12276.1
Integral membrane protein.
 
    
0.547
AKB12274.1
Ribonucleotide reductase of class II (coenzyme B12-dependent); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
 
     0.516
AKB13590.1
Two-component response regulator.
  
  
 0.459
AKB12594.1
Cytochrome c-type biogenesis protein.
 
  
 0.443
AKB12399.1
Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps.
 
  
 0.437
AKB12049.1
Quinolone resistance protein.
 
 
 
 0.428
lolD
Lipoprotein releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
  
  
 0.400
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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