Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AKB12334.1Secreted and surface protein containing fasciclin-like repeats. (242 aa)    
Predicted Functional Partners:
AKB11964.1
NADH-quinone oxidoreductase subunit C/D.
   
 
 0.906
AKB11965.1
NADH-quinone oxidoreductase subunit C/D.
   
 
 0.906
AKB11956.1
NADH:ubiquinone oxidoreductase subunit N.
    
 
 0.661
fpoH
FPO subunit H; FPO shuttles electrons from F(420)H(2), via FAD and iron- sulfur (Fe-S) centers, to quinones in the F(420)H(2):heterodisulfide oxidoreduction chain. The immediate electron acceptor for the enzyme in this species is believed to be methanophenazine. Couples the redox reaction to proton translocation (for every two electrons transferred, 0.9 hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
 
 0.660
AKB11959.1
NADH:ubiquinone oxidoreductase subunit K.
   
   0.646
AKB11966.1
Hypothetical protein.
   
   0.646
AKB11967.1
NADH:ubiquinone oxidoreductase subunit A.
   
   0.646
AKB11957.1
Hypothetical protein.
   
 
 0.572
AKB11960.1
Hypothetical protein.
   
   0.501
AKB11961.1
NADH dehydrogenase subunit J.
   
   0.501
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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