Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB12468.1Energy-conserving hydrogenase (ferredoxin), subunit C. (113 aa)    
Predicted Functional Partners:
AKB14060.1
Energy-conserving hydrogenase (ferredoxin), subunit E.
 
 
 0.988
AKB14062.1
Energy-conserving hydrogenase (ferredoxin), subunit B.
 
 
 0.983
AKB11962.1
Ketoisovalerate oxidoreductase subunit VorD.
 
 
 0.937
AKB14059.1
Energy-conserving hydrogenase (ferredoxin), subunit F.
 
 
 0.909
AKB11964.1
NADH-quinone oxidoreductase subunit C/D.
 
  
 0.821
AKB11885.1
CO dehydrogenase iron-sulfur protein CooF.
  
 
 0.622
AKB11965.1
NADH-quinone oxidoreductase subunit C/D.
 
  
 0.561
AKB14063.1
Energy-conserving hydrogenase (ferredoxin), subunit A.
 
  
 0.488
AKB12467.1
N-methylhydantoinase A/acetone carboxylase, beta subunit.
       0.428
hypA
[NiFe] hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.414
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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