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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB12498.1Response regulator receiver. (291 aa)    
Predicted Functional Partners:
AKB13128.1
Sensory transduction histidine kinase.
 
 
 0.972
AKB13308.1
Sensory transduction histidine kinase.
 
     0.970
AKB12337.1
Sensory transduction histidine kinase.
 
     0.863
AKB13590.1
Two-component response regulator.
 
 
0.854
AKB12499.1
Hypothetical protein.
     
 0.786
AKB13514.1
Sensory transduction histidine kinase.
 
 
0.735
AKB13589.1
Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY.
 
 
 
 0.671
AKB12698.1
Response regulator receiver.
 
 
 
 0.658
AKB11989.1
Response regulator receiver.
 
 
 
 0.647
AKB12243.1
Response regulator receiver.
 
 
 
 0.646
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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