Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB12545.1Hypothetical protein. (556 aa)    
Predicted Functional Partners:
AKB12050.1
S-D-lactoylglutathione methylglyoxal lyase.
 
  
 0.549
AKB14043.1
Protein F12M16.25.
 
     0.547
AKB12544.1
ThiJ/PfpI family protein.
  
  
 0.546
dtdA
D-tyrosyl-tRNA(Tyr) deacylase; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
 
   
 0.533
AKB13699.1
Hypothetical protein.
  
  
 0.492
AKB13549.1
Hypothetical protein.
 
  
 0.473
AKB11843.1
Hypothetical protein.
 
  
 0.455
AKB13447.1
CAAX amino terminal protease family protein.
 
  
 0.451
AKB12017.1
ABC transporter, permease protein.
  
  
 0.443
AKB12209.1
Multidrug ABC transporter, permease protein.
  
  
 0.443
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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