STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB12560.1Ni2+-binding GTPase involved in regulation of expression and maturation of hydrogenase. (234 aa)    
Predicted Functional Partners:
AKB12559.1
Hypothetical protein.
 
  
 0.988
AKB12561.1
Hypothetical protein.
 
    0.984
hypA
[NiFe] hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.862
AKB14060.1
Energy-conserving hydrogenase (ferredoxin), subunit E.
   
 
 0.787
AKB12562.1
Ferredoxin oxidoreductase.
 
     0.759
AKB11935.1
Putative FKBP-type peptidyl-prolyl cis-trans isomerase.
    
 
 0.726
AKB14271.1
Peptidyl-prolyl cis-trans isomerase.
    
 
 0.726
AKB14272.1
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD.
    
 
 0.726
AKB12878.1
[NiFe] hydrogenase metallocenter assembly protein HypC.
  
  
 0.653
AKB12879.1
[NiFe] hydrogenase metallocenter assembly protein HypD.
  
  
 0.644
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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