Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB12561.1Hypothetical protein. (224 aa)    
Predicted Functional Partners:
AKB12559.1
Hypothetical protein.
 
    0.995
AKB12560.1
Ni2+-binding GTPase involved in regulation of expression and maturation of hydrogenase.
 
    0.995
AKB11871.1
Sulfopyruvate decarboxylase - beta subunit.
 
     0.821
AKB12562.1
Ferredoxin oxidoreductase.
 
     0.799
AKB12881.1
[NiFe] hydrogenase nickel incorporation-associated protein HypB.
  
    0.768
AKB11872.1
Cysteate synthase; Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.
 
     0.730
AKB13206.1
Hypothetical protein.
  
     0.669
AKB13668.1
Hypothetical protein.
  
     0.604
AKB12558.1
Biotin synthase-related enzyme.
 
     0.578
AKB12421.1
Transcriptional regulator, ArsR family.
  
     0.537
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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