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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB12565.1Cysteine desulfurase. (91 aa)    
Predicted Functional Partners:
AKB12566.1
Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
   
 0.924
AKB11897.1
Scaffold protein.
  
 0.922
AKB12100.1
Scaffold protein.
  
 0.922
AKB13053.1
Scaffold protein.
  
 0.922
AKB13050.1
Hypothetical protein.
   
 
 0.792
AKB13789.1
Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
   
 0.677
AKB12086.1
Cysteine desulfurase.
  
  
 0.593
thiI
tRNA S(4)U 4-thiouridine synthase (former ThiI); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 
 0.583
AKB12992.1
Putative iron binding protein from the HesB_IscA_SufA family.
  
  
 0.541
AKB13093.1
Quinolinate phosphoribosyltransferase (decarboxylating); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
 
  
 0.510
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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