Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB12565.1Cysteine desulfurase. (91 aa)    
Predicted Functional Partners:
AKB12566.1
Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
   
 0.903
AKB11897.1
Scaffold protein.
  
 0.858
AKB12100.1
Scaffold protein.
  
 0.858
AKB13053.1
Scaffold protein.
  
 0.858
AKB13050.1
Hypothetical protein.
   
 
 0.762
AKB12992.1
Putative iron binding protein from the HesB_IscA_SufA family.
  
 
 0.627
AKB13789.1
Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
   
 0.594
thiI
tRNA S(4)U 4-thiouridine synthase (former ThiI); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 
 0.585
dnaK
Chaperone protein DnaK; Acts as a chaperone.
  
 0.582
AKB12096.1
Serine acetyltransferase; PaaD-like protein (DUF59) involved in Fe-S cluster assembly.
  
  
 0.574
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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