Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB12599.1GTPase Era. (213 aa)    
Predicted Functional Partners:
AKB12598.1
Hypothetical protein.
 
   
 0.987
AKB12597.1
Hypothetical protein.
       0.929
AKB12142.1
Putative ankyrin repeat protein.
  
 0.926
AKB13385.1
Zn-ribbon containing protein.
 
   
 0.862
AKB12596.1
6-phospho-3-hexuloisomerase.
       0.842
AKB11903.1
Serine/threonine protein phosphatase BSU1.
   
 0.828
AKB13947.1
Putative serine/threonine protein phosphatase.
   
 0.828
AKB12595.1
Biosynthetic Aromatic amino acid aminotransferase alpha / Aspartate aminotransferase.
     
 0.819
AKB12981.1
FtsH protease regulator HflK.
  
 0.771
AKB12322.1
Hypothetical protein.
   
 0.755
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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