Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB12711.1Hypothetical protein. (342 aa)    
Predicted Functional Partners:
AKB12710.1
ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase.
 
     0.696
AKB13977.1
Hypothetical protein.
  
     0.672
AKB13312.1
Putative carboxyl-terminal-processing protease, deltaproteobacterial.
  
     0.651
AKB13744.1
Putative transcriptional regulators.
  
     0.625
AKB13435.1
Hypothetical protein.
  
     0.607
AKB14179.1
Nucleotide binding protein, PINc.
  
     0.598
AKB12382.1
Hypothetical protein.
  
     0.593
AKB12737.1
Hypothetical protein.
  
     0.592
AKB13251.1
RecB family exonuclease.
  
     0.591
AKB12340.1
Hypothetical protein.
 
     0.588
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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