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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB12731.1Transcriptional regulator. (428 aa)    
Predicted Functional Partners:
AKB12732.1
Transcriptional regulator.
 
  
 
0.954
AKB12733.1
Transcriptional regulator.
 
  
 
0.937
AKB13553.1
Metallo-beta-lactamase.
    
  0.901
AKB12220.1
Metallo-beta-lactamase family protein.
     
  0.900
AKB13803.1
ATP-utilizing enzyme of the PP-loop superfamily.
 
  
 0.726
AKB13910.1
Circadian phase modifier.
 
  
 0.724
AKB13909.1
Hypothetical protein; Belongs to the LarC family.
 
  
 0.618
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.