Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB12736.1Flagella-related protein FlaI. (862 aa)    
Predicted Functional Partners:
AKB12737.1
Hypothetical protein.
 
     0.958
AKB13808.1
Integral membrane protein.
 
  
 0.743
AKB13742.1
Bipolar DNA helicase.
 
   
 0.587
AKB14215.1
Hypothetical protein.
       0.539
AKB12382.1
Hypothetical protein.
  
     0.530
AKB11921.1
Hypothetical protein.
 
     0.479
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
   
 0.466
AKB13204.1
5-amino-6-(5-phosphoribosylamino)uracil reductase.
 
    0.454
AKB12024.1
Hypothetical protein.
  
     0.418
AKB12372.1
Hypothetical protein.
  
     0.404
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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