STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB12771.1Transcriptional regulator, TrmB family. (83 aa)    
Predicted Functional Partners:
AKB11871.1
Sulfopyruvate decarboxylase - beta subunit.
  
    0.640
AKB12770.1
Transcriptional regulator, TrmB family.
       0.500
AKB12106.1
Iron-sulfur cluster binding protein.
  
    0.483
AKB13742.1
Bipolar DNA helicase.
 
     0.476
AKB13579.1
Origin of replication recognition protein / Cell division control protein 6; Involved in regulation of DNA replication.
 
     0.455
AKB12737.1
Hypothetical protein.
  
     0.447
tfe
Archaeal transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexe [...]
  
   
 0.434
AKB11844.1
Hypothetical protein.
 
   
 0.412
spt4
DNA-directed RNA polymerase subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
  
   
 0.409
AKB12998.1
Putative RNA-processing protein.
  
     0.402
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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