Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB12780.1Acetyl-CoA synthetase (ADP-forming) alpha chain. (455 aa)    
Predicted Functional Partners:
AKB12797.1
Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative.
 
 0.999
AKB12585.1
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase.
    
 0.957
AKB13248.1
Beta-ketoacyl synthase/thiolase.
 
 
 0.931
AKB14284.1
2-oxoglutarate oxidoreductase, alpha subunit.
  
 0.931
AKB13601.1
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
  
 0.927
AKB14283.1
2-oxoglutarate oxidoreductase, beta subunit.
    
 0.919
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.915
AKB12519.1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
    
 0.912
AKB13600.1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
    
 0.912
AKB13602.1
Pyruvate:ferredoxin oxidoreductase, delta subunit.
    
 0.912
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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