Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB12787.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps. (469 aa)    
Predicted Functional Partners:
rpl15
LSU ribosomal protein L27Ae (L15p); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
 
   0.658
AKB12291.1
Transcriptional regulator, MarR family.
 
  
 0.657
AKB12018.1
ABC transporter, ATP-binding protein.
  
  
 0.656
AKB12210.1
ABC transporter, ATP-binding protein.
  
  
 0.656
AKB13316.1
ABC transporter, ATP-binding protein.
  
  
 0.656
tbp
TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
  
 0.644
AKB12788.1
Transcriptional regulator, MarR family.
  
  
 0.569
AKB13590.1
Two-component response regulator.
  
 
 0.562
gap
NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal.
  
  
 0.543
AKB12914.1
SSU ribosomal protein S11e (S17p); Belongs to the universal ribosomal protein uS17 family.
 
 
 
 0.527
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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