Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB13062.1Hypothetical protein. (234 aa)    
Predicted Functional Partners:
AKB11964.1
NADH-quinone oxidoreductase subunit C/D.
  
 0.928
AKB11965.1
NADH-quinone oxidoreductase subunit C/D.
  
 0.928
rps5
SSU ribosomal protein S2e (S5p); With S4 and S12 plays an important role in translational accuracy.
    
 0.648
AKB11966.1
Hypothetical protein.
   
 0.617
AKB12630.1
WD-domain containing protein.
  
 0.604
AKB13063.1
Hypothetical protein.
       0.581
rps9
SSU ribosomal protein S16e (S9p); Belongs to the universal ribosomal protein uS9 family.
  
 
 0.579
rps4
SSU ribosomal protein S9e (S4p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
 
 0.543
rps7
SSU ribosomal protein S5e (S7p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
 
 
 0.525
AKB13947.1
Putative serine/threonine protein phosphatase.
 
 
 
 0.517
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
Server load: medium (44%) [HD]