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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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AKB13338.1Cobalt-precorrin-8x methylmutase. (243 aa)    
Predicted Functional Partners:
AKB13339.1
Cobalt-precorrin-3b C17-methyltransferase.
  
 0.998
AKB13814.1
Cobalt-precorrin-6y C5-methyltransferase.
 
 
 0.998
cbiA
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
 
 0.993
AKB13343.1
Cobalt-precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.992
AKB13342.1
Cobalt-precorrin-4 C11-methyltransferase.
 
  
 0.990
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.988
AKB13340.1
Cobalamin biosynthesis protein CbiG.
 
  
 0.984
AKB13341.1
Cobalamin biosynthesis protein CbiG.
 
  
 0.984
cbiT
Cobalt-precorrin-6y C15-methyltransferase (decarboxylating); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
 
 
 0.983
cbiD
Cobalt-precorrin-6 synthase, anaerobic; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.965
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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