Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB13496.17,8 dihydropteroate synthase (methanopterin). (220 aa)    
Predicted Functional Partners:
AKB12842.1
Dihydropteroate synthase; Alternative dihydrofolate reductase 2.
    
 0.904
mptE
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP).
    
  0.902
AKB12861.1
Nitrogenase reductase-like protein.
 
   
 0.850
AKB12862.1
Hypothetical protein.
 
   
 0.822
AKB13497.1
Transcriptional repressor of nif and glnA operons.
       0.790
AKB12865.1
Hypothetical protein.
 
     0.788
AKB12864.1
Putative transcriptional regulator.
 
     0.738
AKB13333.1
Hypothetical protein.
 
     0.682
AKB12185.1
Hypothetical protein.
 
     0.446
AKB13226.1
Hypothetical protein.
 
     0.442
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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