Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB13557.1Fe-S oxidoreductase; Homology to heterodisulfide reductase 2 iron-sulfur subunit. (390 aa)    
Predicted Functional Partners:
AKB13558.1
FAD/FMN-containing dehydrogenase.
  
 0.992
AKB12620.1
Succinate dehydrogenase flavoprotein subunit.
    
 0.925
AKB12621.1
Succinate dehydrogenase iron-sulfur protein.
  
 0.922
AKB12311.1
Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase beta subunit.
    
 0.917
AKB12310.1
Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase alpha subunit.
    
 0.907
AKB12622.1
Fumarate hydratase class II.
    
  0.901
AKB13560.1
Ribosomal-protein-S18p-alanine acetyltransferase.
       0.668
AKB12133.1
CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
   
 0.658
AKB14118.1
Glutamate synthase [NADPH] small chain.
  
  
 0.520
AKB13330.1
CoB--CoM heterodisulfide reductase subunit C.
 
 
 
 0.469
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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