Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB13691.1Proline 2-methylase for pyrrolysine biosynthesis. (350 aa)    
Predicted Functional Partners:
AKB13690.1
Pyrrolysine synthetase.
 
 
 0.999
AKB13689.1
Proline reductase for pyrrolysine biosynthesis.
 
   
 0.988
pylS
Pyrrolysyl-tRNA synthetase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG.
 
   
 0.984
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
  
 0.932
AKB13803.1
ATP-utilizing enzyme of the PP-loop superfamily.
  
    0.826
AKB13120.1
Trimethylamine:corrinoid methyltransferase; Pyrrolysine-containing; Belongs to the trimethylamine methyltransferase family.
 
   
 0.755
AKB13821.1
Trimethylamine:corrinoid methyltransferase; Pyrrolysine-containing.
 
   
 0.755
AKB11883.1
Membrane protein, putative.
  
    0.722
AKB11843.1
Hypothetical protein.
  
    0.631
AKB13549.1
Hypothetical protein.
  
    0.631
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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