Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB13740.13-isopropylmalate dehydrogenase. (375 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 
 0.998
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.985
AKB14111.1
Acetolactate synthase small subunit.
  
 0.973
AKB14110.1
Acetolactate synthase large subunit.
 
 0.949
AKB12619.1
Acetolactate synthase; Belongs to the TPP enzyme family.
  
 0.942
AKB12519.1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
  
 
 0.907
AKB13600.1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
  
 
 0.907
AKB14283.1
2-oxoglutarate oxidoreductase, beta subunit.
  
 
 0.907
AKB13601.1
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
    
 0.905
AKB13603.1
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
    
 0.905
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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