Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
srp19Signal recognition particle SEC65 subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. (103 aa)    
Predicted Functional Partners:
srp54
Signal recognition particle, subunit Ffh SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
   
 0.994
ftsY
Signal recognition particle 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
   
 
 0.904
rps17e
SSU ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
  
   0.866
rpl30e
LSU ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family.
  
   0.809
rpl15e
LSU ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 
   0.752
rpl37ae
LSU ribosomal protein L37Ae; Binds to the 23S rRNA.
 
   0.744
AKB13760.1
Hypothetical protein.
       0.740
rps3ae
SSU ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
   0.739
rps24e
SSU ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
  
 
 0.715
rpl21e
LSU ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
   0.703
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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