Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
AKB13768.1Hypothetical protein. (352 aa)    
Predicted Functional Partners:
AKB13766.1
Transporter, RND superfamily.
 
  
 0.965
AKB13767.1
Putative carboxyl-terminal-processing protease, deltaproteobacterial.
 
    
0.931
AKB13436.1
Hypothetical protein.
  
     0.697
AKB13312.1
Putative carboxyl-terminal-processing protease, deltaproteobacterial.
 
     0.666
pfkC
ADP-dependent phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
  
     0.648
AKB14046.1
COG4004 family.
  
     0.647
hdrE
CoB--CoM heterodisulfide reductase 2 subunit E; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane. Electrons probably transfer from phenazine to the high potential 4Fe cluster in HdrD subunit, then to the low potential heme in HdrE subunit and finally to CoM-S-S-CoB.
  
     0.639
AKB13656.1
Archaeosortase A.
  
     0.632
AKB12819.1
S-layer family duplication domain protein.
  
     0.604
AKB12816.1
ADP-dependent glucokinase.
  
     0.598
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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