| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB11995.1 | AKB13629.1 | MSTHT_0237 | MSTHT_1871 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.988 |
| AKB11995.1 | AKB13786.1 | MSTHT_0237 | MSTHT_2028 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | 0.645 |
| AKB13422.1 | AKB13786.1 | MSTHT_1664 | MSTHT_2028 | D-arabino-3-hexulose 6-phosphate formaldehyde lyase; Hypothetical protein with distant similarity to Ribonuclease E inhibitor RraA (former MenG). | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | 0.777 |
| AKB13629.1 | AKB11995.1 | MSTHT_1871 | MSTHT_0237 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.988 |
| AKB13629.1 | AKB13786.1 | MSTHT_1871 | MSTHT_2028 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | 0.892 |
| AKB13629.1 | rbcL | MSTHT_1871 | MSTHT_1635 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Ribulose-1,5-bisphosphate carboxylase, Type III; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. | 0.565 |
| AKB13784.1 | AKB13785.1 | MSTHT_2026 | MSTHT_2027 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.854 |
| AKB13784.1 | AKB13786.1 | MSTHT_2026 | MSTHT_2028 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | 0.717 |
| AKB13785.1 | AKB13784.1 | MSTHT_2027 | MSTHT_2026 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | 0.854 |
| AKB13785.1 | AKB13786.1 | MSTHT_2027 | MSTHT_2028 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | 0.835 |
| AKB13785.1 | tpiA | MSTHT_2027 | MSTHT_1786 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.657 |
| AKB13786.1 | AKB11995.1 | MSTHT_2028 | MSTHT_0237 | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.645 |
| AKB13786.1 | AKB13422.1 | MSTHT_2028 | MSTHT_1664 | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | D-arabino-3-hexulose 6-phosphate formaldehyde lyase; Hypothetical protein with distant similarity to Ribonuclease E inhibitor RraA (former MenG). | 0.777 |
| AKB13786.1 | AKB13629.1 | MSTHT_2028 | MSTHT_1871 | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.892 |
| AKB13786.1 | AKB13784.1 | MSTHT_2028 | MSTHT_2026 | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | 0.717 |
| AKB13786.1 | AKB13785.1 | MSTHT_2028 | MSTHT_2027 | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.835 |
| AKB13786.1 | AKB14073.1 | MSTHT_2028 | MSTHT_2315 | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | Fructose-bisphosphate aldolase/6-deoxy-5-ketofructose 1-phosphate synthase. | 0.909 |
| AKB13786.1 | aroA-2 | MSTHT_2028 | MSTHT_1780 | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | 0.909 |
| AKB13786.1 | aroA-3 | MSTHT_2028 | MSTHT_2145 | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | 0.909 |
| AKB13786.1 | rbcL | MSTHT_2028 | MSTHT_1635 | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | Ribulose-1,5-bisphosphate carboxylase, Type III; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. | 0.637 |