Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB13796.1Citrate synthase (si). (355 aa)    
Predicted Functional Partners:
AKB13041.1
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.999
AKB13795.1
Aconitate hydratase.
 
 0.999
AKB13248.1
Beta-ketoacyl synthase/thiolase.
  
 0.982
AKB12585.1
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase.
 
 0.973
AKB12621.1
Succinate dehydrogenase iron-sulfur protein.
 
 
 0.966
AKB12620.1
Succinate dehydrogenase flavoprotein subunit.
 
 
 0.952
AKB14283.1
2-oxoglutarate oxidoreductase, beta subunit.
    
 0.943
AKB12310.1
Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase alpha subunit.
  
 
 0.937
AKB11964.1
NADH-quinone oxidoreductase subunit C/D.
  
 0.935
AKB11965.1
NADH-quinone oxidoreductase subunit C/D.
  
 0.935
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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