Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
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[Homology]
Score
AKB13843.1Sensory transduction histidine kinase. (1006 aa)    
Predicted Functional Partners:
AKB13590.1
Two-component response regulator.
 
 
 0.923
AKB13128.1
Sensory transduction histidine kinase.
 
 
 
 0.863
AKB13844.1
Sensory transduction histidine kinase.
 
   
 0.845
dnaK
Chaperone protein DnaK; Acts as a chaperone.
 
 
 0.719
AKB12332.1
Sensory transduction histidine kinase.
 
   
0.597
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 0.581
AKB12243.1
Response regulator receiver.
 
 
 
 0.550
AKB12698.1
Response regulator receiver.
 
 
 
 0.534
AKB11989.1
Response regulator receiver.
 
 
 
 0.532
AKB12242.1
Response regulator receiver.
 
 
 
 0.523
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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