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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (505 aa)    
Predicted Functional Partners:
hemL
Glutamate-1-semialdehyde aminotransferase.
 
 0.999
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.990
AKB13850.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.981
gltX
Glutamyl-tRNA synthetase / Glutamyl-tRNA(Gln) synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
  
 
 0.952
AKB13848.1
Siroheme synthase; Precorrin-2 oxidase; Sirohydrochlorin ferrochelatase.
 
   
 0.950
AKB14293.1
Uroporphyrinogen-III synthase.
 
  
 0.915
AKB13847.1
Heme biosynthesis protein related to NirL and NirH.
     
 0.862
AKB14294.1
Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.861
AKB13006.1
ChlD component of cobalt chelatase involved in B12 biosynthesis.
 
  
 0.839
AKB13846.1
Heme biosynthesis protein related to NirD and NirG.
     
 0.828
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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