Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB13866.1Hypothetical protein. (167 aa)    
Predicted Functional Partners:
AKB13865.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.831
AKB13864.1
Glycerol dehydrogenase.
 
     0.790
AKB13838.1
Hypothetical protein.
  
     0.720
AKB13042.1
Hypothetical protein.
  
     0.692
AKB13863.1
Replication factor-A protein 1.
 
     0.676
AKB13559.1
Archaeosine tRNA-ribosyltransferase type 2.
  
     0.669
AKB14305.1
Glycerol dehydrogenase.
  
     0.659
AKB14304.1
Replication protein A (two OB fold, one zinc finger).
 
     0.656
AKB14077.1
Hypothetical protein.
 
     0.639
atpF
V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
     0.630
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
Server load: low (20%) [HD]