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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB13885.1tRNA (Guanine37-N1) -methyltransferase. (336 aa)    
Predicted Functional Partners:
trm1
tRNA N2,N2-dimethyl(Guanine26-N2)-methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
  
  
 0.594
dphB
Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
 
  
 0.593
rfcL
Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily.
 
    0.589
rpl15e
LSU ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
  
     0.587
AKB13925.1
rRNA biogenesis protein Nop5/Nop56.
  
  
 0.579
rpoA2
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
    0.572
AKB12998.1
Putative RNA-processing protein.
 
    0.571
AKB14180.1
Eukaryotic translation initiation factor 2 gamma subunit.
 
    0.555
rps3ae
SSU ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
     0.527
AKB13566.1
Replication factor A (ssDNA-binding protein).
  
    0.527
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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